Growth of human breast tissues from patient cells in 3D hydrogel scaffolds. Sokol ES, Miller DH, Breggia A, Spencer KC, Arendt LM, and Gupta PB. Breast Cancer Research. 2016; 18:19. doi: 10.1186/s13058-016-0677-5. [Article]

Comprehensive serological profiling of human populations using a synthetic human virome. Xu GJ, Kula T, Qikai X, Mamie ZL, Vernon SD, Ndung’u T, Rusrungtham K, Sanchez J, Brander C, Chung RT, O’Connor KC, Walker B, Larman HB, Elledge SJ. Science 5. 2015 Jun; 348(6239):1053-1172. doi: 10.1126/science.aaa0698. [Article]

Comprehensive analysis of loops at protein-protein interfaces for macrocycle design. Gavenonis J, Sheneman BA, Siegert TR, Eshelman MR, Kritzer JA. Nat Chem Biol. 2014 Sep;10(9):716-22. doi: 10.1038/nchembio.1580. Epub 2014 Jul 20. [Pubmed]

Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation. Phillips S, Prat A, Sedic M, Proia T, Wronski A, Mazumdar S, Skibinski A, Shirley SH, Perou CM, Gill G, Gupta PB, Kuperwasser C. Stem Cell Reports. 2014 Apr 24;2(5):633-47. doi: 10.1016/j.stemcr.2014.03.008. eCollection 2014.  [Pubmed] [PDF]

The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment. Skibinski A, Breindel JL, Prat A, Galván P, Smith E, Rolfs A, Gupta PB, Labaer J, Kuperwasser C. Cell Rep. 2014 Mar 27;6(6):1059-72. doi: 10.1016/j.celrep.2014.02.038. Epub 2014 Mar 6. [Pubmed] [PDF]

Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis. Arendt LM, McCready J, Keller PJ, Baker DD, Naber SP, Seewaldt V, Kuperwasser C. Cancer Res. 2013 Oct 1;73(19):6080-93. doi: 10.1158/0008-5472.CAN-13-0926. Epub 2013 Aug 19. [PubMed] [PDF]